Search results for "Hajos–Parrish–Eder–Sauer–Wiechert reaction"

showing 3 items of 3 documents

Density functional theory study of the mechanism of the proline-catalyzed intermolecular aldol reaction

2002

Transition structures associated with the C-C bond-formation step of the proline-catalyzed intermolecular aldol reaction between acetone and isobutyraldehyde have been studies using density functional theory methods at the B3LYP/6-31G** computational level. A continuum model has been selected to represent solvent effects. For this step, which is the stereocontrolling and rate-determining step, four reactive channels corresponding to the syn and anti arrangement of the active methylene of the enamine relative to the carboxylic acid group of l-proline and the re and si attack modes to both faces of the aldehyde carbonyl group have been analyzed. The B3LYP/6-31G** energies are in good agreemen…

chemistry.chemical_classificationHajos–Parrish–Eder–Sauer–Wiechert reactionchemistry.chemical_compoundchemistryAldol reactionStereochemistryIntermolecular forceDensity functional theoryPhysical and Theoretical ChemistrySolvent effectsAldehydeIsobutyraldehydeEnamineTheoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta)
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Asymmetric Aldol Reaction with Polystyrene-Supported Proline-Based Catalysts

2009

chemistry.chemical_compoundHajos–Parrish–Eder–Sauer–Wiechert reactionNitroaldol reactionAldol reactionchemistryOrganocatalysisOrganocatalysis proline supported-catalysts aldol reaction proline peptidesOrganic chemistryAldol condensationSettore CHIM/06 - Chimica OrganicaPolystyreneProlineLewis acid catalysisSynfacts
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Asymmetric aldol reaction in water catalyzed by polystyrene-supported proline

2007

chemistry.chemical_compoundHajos–Parrish–Eder–Sauer–Wiechert reactionchemistryAldol reactionOrganocatalysisOrganic chemistryPolystyreneProlineSettore CHIM/06 - Chimica OrganicaSupported organocatalystCatalysis
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